Study record · SLU-PP-332
SLU-PP-332 exercise-mimetic study
SLU-PP-332 increased oxidative muscle features and enhanced exercise endurance in mice through ERR-dependent signalling.
Key result
SLU-PP-332 increased oxidative muscle features and enhanced exercise endurance in mice through ERR-dependent signalling.
Study details
Study designPreclinical mechanistic/animal study
PopulationSkeletal-muscle cells and mice
RoutePreclinical
Regimen / exposureMouse studies included 50 mg/kg dosing in key endurance experiments
DurationAcute and repeated experimental dosing
ComparatorVehicle / genetic controls
Primary endpoint / questionOxidative muscle programme and exercise endurance
Safety resultNo human therapeutic safety information generated.
Key limitationsMouse performance effects cannot establish a human exercise-mimetic benefit or dose.
Registry / identifierPMID 36988910