Study record · Glutathione
Randomized controlled trial of oral glutathione supplementation on body stores of glutathione
Glutathione stores increased in several compartments, generally in a dose- and time-dependent pattern.
Key result
Glutathione stores increased in several compartments, generally in a dose- and time-dependent pattern.
Study details
Study designRandomized, double-blind, placebo-controlled trial
PopulationNon-smoking healthy adults
Sample size54
RouteOral
Regimen / exposure250 mg/day or 1,000 mg/day
Duration6 months
ComparatorPlacebo
Primary endpoint / questionGlutathione concentrations in blood/cells and selected immune/oxidative markers
Safety resultLonger-term oral exposure was studied; this does not establish injectable safety.
Key limitationsBiomarker/target-engagement study; not proof of broad detoxification, longevity or disease prevention.
Registry / identifierPMID 24791752 / NCT01044277