Randomized controlled trial of oral glutathione supplementation on body stores of glutathione
Glutathione stores increased in several compartments, generally in a dose- and time-dependent pattern.
What this study tells us
Participants were assigned to comparison groups by chance, usually with placebo and/or blinding to reduce bias. This is a strong design for testing cause and effect, but the population, duration and endpoints still limit what can be concluded.
Non-smoking healthy adults
n=54
Glutathione stores increased in several compartments, generally in a dose- and time-dependent pattern.
Biomarker/target-engagement study; not proof of broad detoxification, longevity or disease prevention.
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Key result
Glutathione stores increased in several compartments, generally in a dose- and time-dependent pattern.