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Integrity / correction record ยท Dihexa

Retraction of foundational Dihexa HGF/c-Met procognitive paper

The journal retracted the 2014 paper after a Washington State University investigation found falsified and/or fabricated data in figures and related erratum data.

Quick read
Integrity / correction record

What this study tells us

This is a research-integrity record, not a treatment trial. It matters because a retraction or formal correction can change how much weight an older scientific claim should carry.

Who was studied?

Foundational preclinical paper, not a human study

How many?

n=Not applicable

What happened?

The journal retracted the 2014 paper after a Washington State University investigation found falsified and/or fabricated data in figures and related erratum data.

What stops us overclaiming?

Retraction does not prove every Dihexa hypothesis false, but the retracted paper must not support unqualified efficacy/mechanism claims.

Need help with terms such as randomized, placebo, endpoint or sample size? Open the glossary โ†’

Key result

The journal retracted the 2014 paper after a Washington State University investigation found falsified and/or fabricated data in figures and related erratum data.

Study details

Study designResearch-integrity action / formal retraction
PhaseNot applicable
PopulationFoundational preclinical paper, not a human study
Sample sizeNot applicable
RouteNot applicable
Regimen / exposureFormal retraction of 2014 mechanistic/procognitive paper
DurationNot applicable
ComparatorNot applicable
Primary endpoint / questionReliability of foundational HGF/c-Met mechanism evidence
Safety resultNo human safety information is created by this retraction.
Key limitationsRetraction does not prove every Dihexa hypothesis false, but the retracted paper must not support unqualified efficacy/mechanism claims.
Registry / identifierPMID 40312093 / DOI 10.1016/j.jpet.2025.103567