Study record · Dihexa
Retraction of foundational Dihexa HGF/c-Met procognitive paper
The journal retracted the 2014 paper after a Washington State University investigation found falsified and/or fabricated data in figures and related erratum.
Key result
The journal retracted the 2014 paper after a Washington State University investigation found falsified and/or fabricated data in figures and related erratum data.
Study details
Study designResearch-integrity action / formal retraction
PhaseNot applicable
PopulationFoundational preclinical paper, not a human study
Sample sizeNot applicable
RouteNot applicable
Regimen / exposureFormal retraction of 2014 mechanistic/procognitive paper
DurationNot applicable
ComparatorNot applicable
Primary endpoint / questionReliability of foundational HGF/c-Met mechanism evidence
Safety resultNo human safety information is created by this retraction.
Key limitationsRetraction does not prove every Dihexa hypothesis false, but the retracted paper must not support unqualified efficacy/mechanism claims.
Registry / identifierPMID 40312093 / DOI 10.1016/j.jpet.2025.103567