Thymalin added to standard treatment in non-specific pulmonary disease
Thymalin was associated with normalization of lymphocyte count and OKT-4+/OKT-8+ subpopulations; little effect was reported on several other immune measures.
What this study tells us
This study compared groups, which is more informative than an uncontrolled report. The amount of confidence still depends on how the groups were formed, how outcomes were measured and how well bias was controlled.
Patients with non-specific pulmonary diseases
n=35
Thymalin was associated with normalization of lymphocyte count and OKT-4+/OKT-8+ subpopulations; little effect was reported on several other immune measures.
Very small, old Russian study; surrogate immune endpoints and limited generalizability.
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Key result
Thymalin was associated with normalization of lymphocyte count and OKT-4+/OKT-8+ subpopulations; little effect was reported on several other immune measures.