Human evidence record · Acetyl octapeptide-3
Dissolving microneedle anti-wrinkle patch containing acetyl octapeptide-3
The multi-ingredient patch improved several wrinkle/skin parameters versus control.
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Human evidence record
What this study tells us
This study compared groups, which is more informative than an uncontrolled report. The amount of confidence still depends on how the groups were formed, how outcomes were measured and how well bias was controlled.
Who was studied?
Adults with facial wrinkles
How many?
n=24
What happened?
The multi-ingredient patch improved several wrinkle/skin parameters versus control.
What stops us overclaiming?
Because several active ingredients were delivered together, the independent effect of SNAP-8 cannot be isolated.
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Key result
The multi-ingredient patch improved several wrinkle/skin parameters versus control.
Study details
Study designControlled split-face cosmetic clinical study
PhaseNot stated
PopulationAdults with facial wrinkles
Sample size24
RouteTopical/microneedle patch
Regimen / exposureMulti-ingredient patch containing acetyl octapeptide-3 plus other actives
DurationRepeated cosmetic application
ComparatorHyaluronic-acid control side
Primary endpoint / questionWrinkle and skin-imaging outcomes
Safety resultNo major safety concern reported in the small cosmetic study.
Key limitationsBecause several active ingredients were delivered together, the independent effect of SNAP-8 cannot be isolated.
Registry / identifierPMID 39082657
Evidence verified2026-09-18