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Human evidence record ยท Sermorelin

Comparison of GHRH(1-40) and GHRH(1-29)NH2 in young adults and children

GHRH(1-29)NH2 produced GH responses useful for testing pituitary GH reserve; responses varied by underlying diagnosis.

Quick read
Human evidence record

What this study tells us

This was a human pharmacology or physiology study. It can show what the compound does to measured biological signals, but it may not establish a meaningful clinical benefit.

Who was studied?

Young adults plus children/adolescents with suspected GH deficiency

How many?

n=142

What happened?

GHRH(1-29)NH2 produced GH responses useful for testing pituitary GH reserve; responses varied by underlying diagnosis.

What stops us overclaiming?

Diagnostic endocrine testing does not establish anti-ageing, fat-loss or muscle-building efficacy.

Need help with terms such as randomized, placebo, endpoint or sample size? Open the glossary โ†’

Key result

GHRH(1-29)NH2 produced GH responses useful for testing pituitary GH reserve; responses varied by underlying diagnosis.

Study details

Study designHuman diagnostic/physiology study
PopulationYoung adults plus children/adolescents with suspected GH deficiency
Sample size142
RouteIntravenous
Regimen / exposure1 microgram/kg GHRH(1-29)NH2 in diagnostic testing
DurationAcute test
ComparatorGHRH(1-40) / clinical diagnostic context
Primary endpoint / questionGrowth-hormone reserve
Safety resultAcute testing context; no long-term lifestyle safety information.
Key limitationsDiagnostic endocrine testing does not establish anti-ageing, fat-loss or muscle-building efficacy.
Registry / identifierPMID 2880720