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Human evidence record · Selank

Selank versus medazepam in generalized anxiety disorder and neurasthenia

Selank and medazepam produced similar anxiolytic effects; authors also reported antiasthenic/psychostimulant effects with Selank.

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Human evidence record

What this study tells us

Participants were assigned to groups by chance, which helps reduce selection bias. The exact comparator, blinding, population and endpoint still matter when judging the result.

Who was studied?

Adults with GAD and neurasthenia

How many?

n=62

What happened?

Selank and medazepam produced similar anxiolytic effects; authors also reported antiasthenic/psychostimulant effects with Selank.

What stops us overclaiming?

Older single-region literature; limited independent replication and incomplete modern reporting standards.

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Key result

Selank and medazepam produced similar anxiolytic effects; authors also reported antiasthenic/psychostimulant effects with Selank.

Study details

Study designRandomized comparative clinical study
PhaseNot stated
PopulationAdults with GAD and neurasthenia
Sample size62
RouteIntranasal (regional clinical use)
Regimen / exposureSelank regimen as used in the original regional study
DurationStudy course
ComparatorMedazepam
Primary endpoint / questionAnxiety and psychometric scales
Safety resultInternational long-term safety data remain limited.
Key limitationsOlder single-region literature; limited independent replication and incomplete modern reporting standards.
Registry / identifierPMID 18454096
Evidence verified2026-09-18