Study record · Modified GRF(1-29) / 'CJC without DAC'
GHRH(1-29) and D-Ala2 analogue GH-response study
Both peptides stimulated GH; the D-Ala2 analogue was approximately twice as potent as native GHRH(1-29) in this small study.
Key result
Both peptides stimulated GH; the D-Ala2 analogue was approximately twice as potent as native GHRH(1-29) in this small study.
Study details
Study designHuman dose-response pharmacology
PopulationNormal men
Sample size5
RouteIntravenous bolus
Regimen / exposure0.015 to 0.5 micrograms/kg
DurationSingle-dose challenges
ComparatorVehicle / native GHRH
Primary endpoint / questionGrowth-hormone response
Safety resultTransient flushing occurred at the highest dose; no other side effects were noted.
Key limitationsAgain this is not the tetrasubstituted Mod GRF(1-29) sold as CJC no-DAC.
Registry / identifierPMID 2866496