Study record · PEG-MGF
MGF peptide replication study in myoblasts and muscle stem cells
The investigators found no apparent proliferative or differentiation effect and questioned earlier claims for the peptide.
Key result
The investigators found no apparent proliferative or differentiation effect and questioned earlier claims for the peptide.
Study details
Study designIn-vitro replication / null study
PopulationC2C12 cells, primary human myoblasts and mouse muscle stem cells
RouteIn vitro
Regimen / exposureNative/stabilized MGF peptide
DurationCell-culture experiment
ComparatorVehicle / positive controls
Primary endpoint / questionMyoblast proliferation/differentiation
Safety resultNo human administration or safety data.
Key limitationsNot PEG-MGF; nevertheless it is important conflicting evidence against transferring a simple MGF growth narrative to commercial products.
Registry / identifierPMID 24253050