WhichPeps
Study record · Kisspeptin

Kisspeptin administration in women with hypoactive sexual desire disorder

Kisspeptin modulated sexual/emotional brain processing; 32 participants completed evaluable crossover testing.

Key result

Kisspeptin modulated sexual/emotional brain processing; 32 participants completed evaluable crossover testing.

Study details

Study designRandomized double-blind placebo-controlled crossover study
PopulationWomen with HSDD
Sample size40
RouteIntravenous infusion
Regimen / exposureKisspeptin-54 at 1 nmol/kg/hour
Duration75 minutes
ComparatorPlacebo
Primary endpoint / questionSexual brain processing and psychometric responses
Safety resultNo major acute adverse effects reported.
Key limitationsShort mechanistic study; not a long-term clinical-outcome trial.
Registry / identifierPMID 36287566