Study record · Kisspeptin
Kisspeptin administration in men with hypoactive sexual desire disorder
Kisspeptin altered sexual/emotional brain processing and increased penile tumescence in experimental conditions.
Key result
Kisspeptin altered sexual/emotional brain processing and increased penile tumescence in experimental conditions.
Study details
Study designRandomized double-blind placebo-controlled crossover study
PopulationMen with HSDD
Sample size37
RouteIntravenous infusion
Regimen / exposureKisspeptin-54 at 1 nmol/kg/hour
Duration75 minutes
ComparatorPlacebo
Primary endpoint / questionSexual brain processing and physiological arousal
Safety resultNo major acute safety signal reported in the paper.
Key limitationsSmall mechanistic study; short exposure; does not establish long-term clinical efficacy or a routine treatment regimen.
Registry / identifierPMID 36735255