Study record · Hexarelin
Hexarelin-induced GH, cortisol and prolactin release: dose-response study
Hexarelin produced dose-dependent GH and prolactin responses and a cortisol increase at higher doses; low-dose hexarelin was synergistic with GHRH for GH.
Key result
Hexarelin produced dose-dependent GH and prolactin responses and a cortisol increase at higher doses; low-dose hexarelin was synergistic with GHRH for GH release.
Study details
Study designDose-response human physiology study
PopulationHealthy adult men
Sample sizeSmall study
RouteIntravenous
Regimen / exposure0–1.0 microg/kg; additional GHRH combination condition
DurationSingle exposure
ComparatorDose conditions / GHRH
Primary endpoint / questionGH, prolactin and cortisol responses
Safety resultNon-GH endocrine activation is clinically relevant.
Key limitationsAcute small study; no evidence for long-term performance, recovery or anti-ageing benefit.
Registry / identifierPMID 8954038