Study record · GHRP-6
GHRP-6 stimulates sleep, GH, ACTH and cortisol release in normal men
GHRP-6 increased GH, ACTH, cortisol and stage-2 sleep; slow-wave sleep was unchanged.
Key result
GHRP-6 increased GH, ACTH, cortisol and stage-2 sleep; slow-wave sleep was unchanged.
Study details
Study designPlacebo-controlled sleep/endocrine physiology study
PopulationHealthy men
Sample sizeSmall study
RouteIntravenous
Regimen / exposureFour 50 microg boluses during the night
DurationOvernight
ComparatorPlacebo
Primary endpoint / questionSleep EEG plus GH, ACTH and cortisol secretion
Safety resultACTH/cortisol stimulation shows endocrine effects beyond GH.
Key limitationsSmall old physiology study; no evidence for durable sleep treatment or physique benefit.
Registry / identifierPMID 7617137