Study record · GHRP-6
Route-dependent sleep/endocrine effects of GHRP-6
Oral dosing did not change GH/ACTH/cortisol; intranasal dosing increased GH and showed route-dependent endocrine/sleep effects.
Key result
Oral dosing did not change GH/ACTH/cortisol; intranasal dosing increased GH and showed route-dependent endocrine/sleep effects.
Study details
Study designPlacebo-controlled route-comparison physiology study
PopulationHealthy young men
Sample sizeSmall study
RouteOral / intranasal / sublingual
Regimen / exposure300 microg/kg oral; 30 microg/kg intranasal or sublingual
DurationOvernight
ComparatorPlacebo conditions
Primary endpoint / questionGH, ACTH, cortisol and sleep effects by route
Safety resultRoute materially changed biological activity.
Key limitationsSmall acute study; old formulation-specific data and no therapeutic clinical outcomes.
Registry / identifierPMID 10336729