Cerebrolysin enhances cognitive recovery of mild traumatic brain injury patients
CASI improvement from baseline to week 12 was greater with Cerebrolysin (21.0 vs 7.6; p=0.0461).
What this study tells us
Participants were assigned to comparison groups by chance, usually with placebo and/or blinding to reduce bias. This is a strong design for testing cause and effect, but the population, duration and endpoints still limit what can be concluded.
Adults with acute mild TBI and intracranial contusion haemorrhage
n=32
CASI improvement from baseline to week 12 was greater with Cerebrolysin (21.0 vs 7.6; p=0.0461).
Very small N; multiple cognitive domains; borderline primary comparison; requires replication.
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Key result
CASI improvement from baseline to week 12 was greater with Cerebrolysin (21.0 vs 7.6; p=0.0461).