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Review / evidence synthesis ยท BPC-157

BPC-157 as an Emerging Therapy in Orthopedic Sports Medicine: A Systematic Review

35 of 36 included studies were preclinical and only one was clinical; preclinical signals were promising but human evidence was extremely sparse.

Quick read
Review / evidence synthesis

What this study tells us

This study reviewed or combined evidence from multiple studies. It can show the overall direction of a field, but its conclusion still depends on the quality and relevance of the studies it included.

Who was studied?

Published BPC-157 studies relevant to orthopaedic/sports medicine

How many?

36 included studies (not 36 recruited participants)

What happened?

35 of 36 included studies were preclinical and only one was clinical; preclinical signals were promising but human evidence was extremely sparse.

What stops us overclaiming?

Heterogeneous preclinical models; very limited human evidence; publication bias possible.

Need help with terms such as randomized, placebo, endpoint or sample size? Open the glossary โ†’

Key result

35 of 36 included studies were preclinical and only one was clinical; preclinical signals were promising but human evidence was extremely sparse.

Study details

Study designSystematic review
PhaseNot applicable
PopulationPublished BPC-157 studies relevant to orthopaedic/sports medicine
Sample size36
RouteMultiple / mostly preclinical
Regimen / exposureVaried
DurationVaried
ComparatorVaried
Primary endpoint / questionState of evidence for musculoskeletal uses
Safety resultReview highlighted lack of established clinical safety data.
Key limitationsHeterogeneous preclinical models; very limited human evidence; publication bias possible.
Registry / identifierPMID 40756949