Study record · Semax
Semax during early and late rehabilitation after ischemic stroke
Semax groups showed increased plasma BDNF and were reported to have faster improvement / better Barthel outcomes.
Key result
Semax groups showed increased plasma BDNF and were reported to have faster improvement / better Barthel outcomes.
Study details
Study designComparative clinical rehabilitation study
PopulationPatients in early or late rehabilitation after ischemic stroke
Sample size110
RouteClinical Semax formulation
Regimen / exposureTwo 10-day courses, 6000 mcg/day, separated by 20 days
DurationStudy-period rehabilitation follow-up
ComparatorStandard rehabilitation without Semax
Primary endpoint / questionBDNF, motor performance and Barthel Index
Safety resultNo modern large-scale safety dataset was generated.
Key limitationsNon-blinded/older regional rehabilitation evidence; biomarker changes do not independently establish neuroprotection.
Registry / identifierPMID 29798983